Carotid Artery Disease & Stroke Prevention
Each year more than 500,000 people become the new stroke victims in the U.S. It is the third leading cause of death in the U.S. and it is responsible for some of the biggest expenditures in health care dollars in America. Not to mention there is an enormous incalculable cost in lifestyle adjustment and rehabilitation to the individual and their family in a patient who has had a stroke.
Stroke is a disease of the blood vessels that affects the brain. A stroke occurs when a blood vessel to the brain suddenly bursts or becomes blocked. This part of the brain then begins to die. Nerves from this part of the brain no longer have control over part of the body. The result is usually permanent because the body cannot replace brain cells. Such brain injury may affect the ability to speak, to move the arms, to move the legs or to move the facial muscles. A stroke may affect behavior patterns, thoughts, memory, emotions, or sensations. Paralysis or weakness of one side of the body is common.
What is Carotid Artery Disease?
Carotid artery stenosis is the narrowing of the carotid arteries. The carotid arteries are the main arteries in the neck that supply blood to the brain. When atherosclerotic plaques develop in the arteries, the carotid arteries are often involved, causing the narrowing. These plaques are formed from cholesterol, fat and other substances that arise from the lining of the arteries. These atherosclerotic plaques in the carotid arteries are a risk factor for stroke.
Symptoms of Carotid Artery Disease
Carotid artery stenosis may or may not cause symptoms. A doctor may hear an abnormal sound when listening to the artery with a stethoscope. Carotid ultrasonography may also detect the stenosis by placing an ultrasound probe on the neck.
Treatment Options for Carotid Artery Disease
Treatment of carotid artery stenosis depends on the degree of narrowing in the blood vessel. The greater the degree of stenosis, the more likely that a stroke will occur. Treatment of the stenosis may result in a dramatic reduction in the chance of stroke. Treatment regimens include medications, plaque removal, and plaque dilatation.
Medication for the treatment of carotid plaques includes classes of drugs known as antiplatlet agents and cholesterol lowering agents. Antiplatlet agents such as aspirin reduce clots in the blood vessels. Cholesterol lowering agents known as statins control levels of blood cholesterol and may decrease the inflammation of the plaques. Medical treatment of hypertension and diabetes also prevents strokes.
Medical therapy is the first line treatment of carotid stenosis and should be used for most blockages less than 50%. Narrowing of carotid arteries greater than 70% or plaques with dangerous ulcers should be considered for more aggressive therapies. These plaques are treated with procedures to remove the blockages. Treatment has the potential to reduce relative stroke risk by over 70%.The most commonly performed procedure is known as carotid endarterectomy. Carotid endarterectomy removes all of the plaque that caused the artery to narrow. These procedures have been shown to reduce the risk of stroke by between 50 and 70%. Another treatment is carotid artery stenting, which uses balloons and stents to dilate the plaques. This method is particularly useful for high-risk patients or plaques in unusual places.
